Metabolism of Starvation during coronavirus lockdown reduces the ability to fight COVID-19: Hit’s The Nation hard,2020

Starvation is generally a condition that occurs due to the food scarcity or the desire to rapidly lose weight or any clinical condition which engages surgery, burns. Starvation is metabolism stress which imposes different metabolic conditions to adapt to the state of lack of food. Glucose is the central metabolic fuel for the production of energy to muscles, brain, and tissue, etc for carrying the metabolic condition but generally, the carbohydrates have a low reserve that can't maintain the body’s energy requirement. 

Triacylglycerol is predominantly high which helps as a good reserve for energy requirements. The survival time of an individual is dependent only on the body fat, these help the obese individuals to survive more than the lean ones.

Proteins are the structural constituents mostly present in the muscles .during starvation the proteins also helps to meet the energy demands of the body. Starvation is also associated with the increase in the glucagon levels in the blood and antagonist effect on insulin levels.

Effect of different Organs : 

1. Liver in starvation : 

• carbohydrate metabolism - the action of the liver is to act as blood glucose buffering organ. During starvation, the gluconeogenesis levels increases as the glucose formation and elevated glycogen degradation furnish glucose to the needy tissues. 

• lipid metabolism - elevated ketone bodies  level 

• as the liver is the hematopoietic organ 

• reduces the immune build-up 

• decreases building antibody 

• generally involved in important metabolic reactions 

2. Adipose tissue in starvation :

• carbohydrate metabolism: glucose uptake and its metabolism is lowered 

• lipid metabolism: TG levels are increased to release fatty acids and glycerol 

• storage of fats 

3. Skeletal  muscles in starvation :

• Carbohydrate metabolism: glucose uptake and metabolism are reduced 

• lipid metabolism: both fatty acids and ketone bodies utilized